13th – 16th May 2007
2nd Paris Workshop on Molecular and Statistical Genomic Epidemiology
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| Day 1 - 13th May 2007 | |||
| 16:00-18:00 Inscription | |||
| 18:00-19:00 | Welcome cocktail | ||
| Day 2 - 14th May 2007 | |||
| 8:30-8:40 | Introduction | Mark Lathrop | |
| Session 1: | Methods for DNA and RNA variation analysis | ||
| 8:40-9:20 | Methods for DNA variation analysis | Ivo Gut | |
| 9:20-9:35 | Epigenomics - DNA methylation analysis | Jörg Tost | |
| 9:50-10:05 | Solexa 1G sequencing | NN | |
| 10:05-10:20 | SOliD sequencing | Michael Rhodes | |
| 10:20-10:30 | Geniom: Customized microfluidics microarrays | Ioannis Amarantos |
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10:30-10:55 |
Coffee Break |
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| 10:55-11:05 | APEX-2, flexible medium-scale genotyping | Kaarel Krjutskov |
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| 11:05-11:15 | A bead-based approach for for RNA selection | Daniel Klevebrin |
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| Session 2: | Methods for protein and metabolite variation analysis | ||
| 11:15-11:55 | From proteomics biomarker discovery to validation | Hanno Langen | |
| 11:55-12:35 | Technology improvements to measure interaction screening on protein arrays | Dolores Cahill | |
12:35-14:00 |
Lunch |
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| Session 2: | Continued | ||
| 14:00-14:10 | An anatomically comprehensive analysis of human protein profiles in normal and cancer tissues | Marcus Gry Björklund | |
| 14:10-14:50 | Cell Arrays | Olli Kallioniemi | |
| 14:50-15:30 | The genetics of metabolic profiles in animal models of insulin resistance | Marc Dumas | |
| Session 3: | Disease genetics I | ||
| 15:30-16:00 | Genome-wide association study of Crohn's disease | Mark Lathrop |
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16:00-16:30 |
Coffee Break |
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| 16:30-17:10 | The Wellcome Trust Case/Control study | David Clayton | |
| 17:10-17:25 | WGA: Variants influencing steroid hormene levels | David Cox | |
| 17:25-17:35 | WGA for blood pressure traits | Elin Org | |
| 17:35-17:50 | The BRIGHT study | NN | |
| Day 3 - 15th May 2007 | |||
| Session 4: | Genetic variation & biological function I | ||
| 9:00-9:40 | Gene-gene interactions | Jürg Ott | |
| 9:40-10:20 | Computational Methods for Genome-wide Prediction of Imprinted Genes | Alex Hartemink | |
10:20-10:45 |
Coffee Break |
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| 10:45-11:25 | Causes of regulatory variation in the human genome | Manolis Dermitzakis | |
| 11:25-11:35 | A micro-RNA view on the evolution of human gene regulation | Helene Quach | |
| 11:35-11:45 | Synovial joint variability and effect of blocking TNF-alpha in RA | Johan Lindberg |
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| 11:45-11:55 | N-acetyltransferase 8: A novel blood pressure and kidney function associated gene | Peeter Juhanson | |
| 11:55-12:05 | Natural selection and innate immunity: Human toll-like receptor signalling pathway | Etienne Patin |
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| 12:05-12:15 | Association between APOE and carotid intima media thickness but not leukoaraiosis suggests a specific association with large artery stroke | Lavinia Paternoster |
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12:15-13:35 |
Lunch |
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| Session 5: | Biobanking & MOLPAGE | ||
| 13:35-14:15 | Data warehousing & medical genomics | Alvis Brazma | |
| 14:15-14:55 | Biobanking | Tim Peakman | |
| 14:55-15:35 | Inferring Copy Number Polymorphisms from Illumina BeadChip SNP genotyping data | Chris Holmes | |
15:35-16:00 |
Coffee Break |
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| Session 6: | Disease genetics II | ||
| 16:00-16:40 | Type 2 diabetes and obesity: genetics and genomics | Mark McCarthy | |
| 16:40-17:20 | Genetics of Asthma and Allergies | Michael Kabesch | |
| 17:20-18:00 | Breast cancer | Doug Easton | |
| Day 4 - 16th May 2007 | |||
| Session 7: | Genetic variation & biological function II | ||
| 9:00-9:40 | Statistical analysis of array data | Terry Speed | |
| 9:40-10:20 | Weighted Gene Co-Expression Network Analysis in the Era of Genomic Epidemiology | Steve Horvath | |
| 10:20-10:35 | Affymetrix | Dirk Jürgensen |
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| 10:35-10:45 | Berardinelli-Seip congenital lipodystrophy due to Caveolin-1 disruption | Jocelyne Magre |
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| 10:45-10:55 | Identification of a fifth gene involved in autosomal dominant hypercholesterolemia | Mathilde Varet |
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10:55-11:20 |
Coffee Break |
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| 11:20-12:00 | Expression analysis & disease | Eric Schadt | |
| 12:00-12:10 | Genetics of bipolar disorder in a large Scottish family | Lorna Houlihan | |
| 12:10-12:20 | Association analysis of the chromosome 4p15-16 candidate region in bipolar affective disorder and schizophrenia | Andrea Christoforou | |
12:20-13:40 |
Lunch |
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| Session 8: | Study design |
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| 13:40-14:20 | A genome-wide expression/ genetic variant database | Goncalo Abecasis | |
| 14:20-14:30 | A two-step approach for genome-wide association studies, comparison of alternative strategies | Hugues Aschard |
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| 14:30-14:40 | A Bayesian measure of the probability of false discovery | Jon Wakefield |
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| Session 9: | Discussion of topics | ||
| 14:40-15:00 | A novel sequence database | Simon Heath | |
| 15:00-15:40 | Survey of statistical and bioinformatics issues | Dan Weeks | |
| 15:40-16:00 | Conclusions | Mark Lathrop / Ivo Gut / Dan Weeks |
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